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✅ Active Ingredients

Polynucleotides PN (DNA + RNA) — Broad-Spectrum Biological Regeneration Agent

Polynucleotides have a wide spectrum of action: they activate general cellular metabolism, normalise local skin immunity, stimulate production of dermal structural components — fibroblasts produce collagen, elastin, and hyaluronic acid, which determine skin elasticity and resilience. They also block photodam­age to the cell’s own DNA, reducing the number of atypical cells, and regulate melanogenesis by stabilising cell membranes, significantly reducing cellular sensitivity to the harmful effects of chemicals and radiation.

Acetyl Hexapeptide-8 — Botox-like Smoothing Peptide

Specifically designed to combat facial wrinkles. Effectively reduces wrinkles on the neck and around the eyes, and not only reduces existing wrinkles but also prevents the formation of new ones. A low-molecular-weight biomimetic peptide with a botox-like mechanism — it is an acetylcholine inhibitor that blocks the impulse at the neuromuscular junction, leading to relaxation of expression muscles and smoothing of dynamic wrinkles. A synthetic substance that is non-toxic, which is a significant advantage of this product.

L-Proline — Endogenous Collagen Amino Acid

An endogenous amino acid that plays a key role in collagen production. Delivers strong anti-aging and anti-wrinkle action — firms, tightens, and improves skin elasticity; renews collagen fibres; reduces skin laxity and improves facial oval; eliminates stretch marks and reduces wrinkles.

Non-Cross-Linked Hyaluronic Acid (36 mg in 3 ml, average molecular weight 1400 to 2200 kDa) — Latest Generation Volumetric HA

The latest generation of non-cross-linked hyaluronic acid, with an average molecular weight of 1400 to 2200 kDa. At this concentration of 36 mg in 3 ml, composed of two high molecular weight HA molecules, it not only hydrates but provides an immediate intradermal filler-like volumetric effect on the face, neck, and hands. Produced to recreate the basic structure of the extracellular matrix (ECM). Continues to nourish and hydrate the skin for several days after the treatment.

Small Peptides — Hydrating & Comfort Agents

Provide skin hydration and soothe discomfort during the action of other active substances in the skin.

✅ Indications

• Loss of facial volume and definition
• Loss of skin tension, density, and elasticity
• Expression and static wrinkles on the face, neck, and around the eyes
• Skin requiring collagen and elastin stimulation
• Dehydrated skin
• Pigmentation of various origins including post-traumatic
• Skin requiring biological renewal and tissue regeneration
• Neck laxity and crepey skin
• Loss of skin firmness on the hands

✅ Mechanism of Action

The preparation works simultaneously on multiple levels. Polynucleotides activate cellular metabolism and stimulate fibroblasts to produce collagen, elastin, and hyaluronic acid while blocking photodam­age and regulating melanogenesis. The botox-like Acetyl Hexapeptide-8 relaxes expression muscles by blocking the neuromuscular impulse. L-Proline directly provides the key building block for collagen fibre synthesis. The high molecular weight non-cross-linked HA at 36 mg/3 ml provides an immediate intradermal volumetric effect while simultaneously recreating ECM structure and delivering prolonged hydration for several days post-treatment.

✅ Treatment Effects

• Repair and reconstruction of the skin
• Strengthening of barrier properties and local cellular immunity
• Firming and tightening of the skin with deep hydration
• Reduction of pigmentation of various origins and normalisation of melanogenesis
• Stimulation of collagen and elastin synthesis
• Significant smoothing of facial wrinkles
• Immediate visible volumetric effect after treatment
• Long-term regenerative effect preserved alongside the volumetric result
• Treatment is short, almost painless, and leaves no marks

✅ Treatment Areas

• Face (full face, cheeks, perioral area, jawline)
• Eyes and periorbital area
• Neck
• Décolletage
• Hands

✅ Key Benefits

• Immediate volumetric effect: The high molecular weight HA at 36 mg/3 ml delivers a visible intradermal filler-like effect from the first treatment while preserving a natural appearance.
• Long-term biological regeneration: Polynucleotides ensure the sustained collagen, elastin, and HA production stimulus that classic mesotherapy provides — both effects are achieved in a single preparation.
• Botox-like action without toxin: Acetyl Hexapeptide-8 inhibits the neuromuscular impulse and smooths expression wrinkles through a non-toxic synthetic biomimetic mechanism.
• Latest generation HA: The 1400 to 2200 kDa molecular weight range with 36 mg/3 ml concentration provides both hydration and volumetric lifting — not achievable with standard mesotherapy HA concentrations.
• ECM reconstruction: The HA component is specifically formulated to recreate the extracellular matrix structure and continues hydrating and nourishing the skin for several days after the session.
• Minimal injection points: The 5-point aesthetic schema allows full facial volumetry and stimulation with as few as 5 to 6 injections per side.
• Versatile application: Can be applied with needle or cannula across face, neck, décolletage, and hands.