Lumina PDRN

Opis

✅ Active Ingredients

Lightly Cross-linked Hyaluronic Acid (Shiseido Technology) — Soft Filler, Hydration, Elastic Support Creates a three-dimensional network with very light viscosity, delivering a soft lifting effect. Fills superficial grooves and gently rebuilds volume without burdening the tissues or migrating — very high stability level. The gel consistency allows precise application even in thin-skinned areas. Shiseido technology ensures high purity, even molecular distribution, and absence of swelling. Smooths expression wrinkles, improves tissue elasticity, supports epidermal reconstruction, and prepares the skin for more intensive stimulation.

PDRN — Sodium Polyribonucleotide — DNA Regeneration, Tissue Repair, Ligament Booster Activates A2A receptors, producing a strong anti-inflammatory effect. Stimulates fibroblasts to produce type I and III collagen. Improves blood supply and tissue metabolism. Accelerates regeneration of facial ligaments including check ligaments, mandibular ligament, and zygomatic ligament. Clinical benefits include increased firmness and elasticity, improved soft tissue support, skin density reconstruction, and excellent action in lax zones such as the neck, hands, and perioral area.

Acetyl Hexapeptide-8 — Botox-like Peptide — Muscle Tension Reduction, Wrinkle Smoothing Inhibits the release of catecholamines and acetylcholine. Reduces the intensity of facial expressions. Gently smooths marionette lines, crow’s feet, and transverse wrinkles. Ideal for patients apprehensive about botulinum toxin — delivers smoothing without freezing, with a synergistic effect alongside HA and PDRN.

Palmitoyl Pentapeptide-4 — Repair Peptide, Anti-Aging Activates fibroblasts for intensive collagen synthesis. Increases skin thickness and its resistance to laxity. Acts as a “skin within the skin” — rebuilding the structural scaffold.

Phosphate-Buffered Saline (PBS) — Stability, Biocompatibility, Safe pH Ensures a stable environment for all active ingredients. Minimizes the risk of irritation and adverse reactions. Supports even distribution of the preparation in the tissues.

✅ Indications

• Patients requiring subtle structural lifting without the heaviness of classic fillers
• Improvement of facial profile
• Tissue and ligament regeneration
• Loss of tissue support at the jawline
• Loss of volume in the temples
• Loss of support in the marionette line and nasolabial fold area
• Natural results without the risk of overcorrection
• Skin laxity, low skin density, and dehydration in the neck area
• Hand revitalization and improvement of skin hydration and thickness
• Fine grooves and uneven skin in the décolletage area

✅ Mechanism of Action

The preparation acts as a hybrid of soft filler and biostimulator through three simultaneous mechanisms.

Soft filling: The lightly cross-linked Shiseido HA creates a three-dimensional gel network that gently fills superficial grooves and rebuilds subtle volume without tissue loading or migration.

Biostimulation and regeneration: PDRN activates A2A receptors, stimulating fibroblasts to increase collagen type I and III production, improving microcirculation, and accelerating ligament regeneration. Palmitoyl Pentapeptide-4 further activates fibroblasts for intensive collagen synthesis and increases skin thickness.

Neuromodulatory smoothing: Acetyl Hexapeptide-8 inhibits catecholamine and acetylcholine release, reducing expression muscle intensity and gently smoothing dynamic wrinkles without paralysis.

The combination of gel HA consistency, regenerative PDRN, and smoothing and rebuilding peptides creates a hybrid that gently lifts, firms, regenerates, hydrates, tightens, rejuvenates, and brightens. For facial ligaments specifically, the preparation improves tissue density around ligament attachment points, reinforces their support, stabilizes the structure of the cheek, jawline, and temples, and extends the lifting effect of other preparations.

✅ Treatment Effects

• Soft lifting and gentle elevation of facial structures
• Smoothing of superficial grooves and wrinkles without the heaviness of classic fillers
• Improvement of facial profile and tissue quality
• Firmness, elasticity, and radiance
• Improved support of soft tissues around facial ligaments
• Stabilization of cheek structure, jawline, and temples
• Extension of the lifting effect achieved with other preparations
• Revitalization of hands: filling of skin grooves, improvement of hydration and skin thickness
• Improvement of neck skin: smoothing of neck creases and transverse wrinkles, improvement of skin density
• Smoothing and unification of décolletage skin
• Effects described as soft, elegant, harmonious, subtle, and long-lasting

✅ Treatment Areas

Face:

• Nasolabial folds (gentle soft filler effect)
• Marionette lines
• Temple area
• Cheek area (subtle volume and glow)
• Perioral area (support without overcorrection)
• Smoker’s lines (soft resurfacing)

Neck:

• Neck creases and transverse wrinkles
• Skin laxity and low skin density

Hands:

• Revitalization, filling of skin grooves
• Improvement of hydration and skin thickness

Décolletage:

• Fine grooves
• Skin unification and hydration

✅ Key Benefits

The Art of Soft Enhancement — Soft Filler and Biostimulator in one: The combination of gel HA consistency, regenerative PDRN, and smoothing and rebuilding peptides creates a hybrid that delivers gentle lifting, firming, regeneration, hydration, tightening, rejuvenation, and brightening in a single preparation.

Shiseido lightly cross-linked HA technology: High purity, even molecular distribution, absence of swelling, and very high stability — does not migrate, does not burden tissues, and allows precise application even in delicate thin-skinned zones.

PDRN as Ligament Booster: Accelerates regeneration of facial ligaments (check ligaments, mandibular ligament, zygomatic ligament), improves tissue density around ligament attachment points, and reinforces structural support — an action not available in standard skin boosters.

Botox-like effect without toxin: Acetyl Hexapeptide-8 gently reduces expression muscle intensity without paralysis, ideal for patients apprehensive about botulinum toxin.

Natural results: The effect is exceptionally natural — the patient looks rested, not post-procedure. Suitable for those who want to improve facial profile and tissue quality without the risk of overcorrection

✅ Contraindications

Do not use in:

• Areas of severe lymphatic swelling
• Patients with active inflammation or infection
• Areas with active PMMA granulomas, silicone, or similar materials
• Pregnancy and breastfeeding

Use with caution in:

• Periorbital area (microboluses only, not linear technique)
• Patients with coagulation disorders
• Patients after intensive laser or deep peeling within the last 14 days
• Avoid injecting too deeply — this is not a classic filler

✅ Storage

Store at 3°C to 25°C in a dry place, protected from light and freezing. Do not use if the package is damaged or expired.