{"id":3598,"date":"2026-04-13T19:38:04","date_gmt":"2026-04-13T17:38:04","guid":{"rendered":"https:\/\/belvisodrhoa.com\/product\/toxup\/"},"modified":"2026-06-24T22:36:28","modified_gmt":"2026-06-24T20:36:28","slug":"toxup","status":"publish","type":"product","link":"https:\/\/belvisodrhoa.com\/pl\/catalogue\/mesotherapy\/toxup\/","title":{"rendered":"ToxUp"},"content":{"rendered":"

\u2705 Active Ingredients<\/strong><\/p>\n

Acetyl Hexapeptide-8<\/strong> (also known as Argireline) \u2014 Botox-like Neuromodulatory Peptide<\/em><\/p>\n

A biomimetic peptide that inhibits the release of neurotransmitters responsible for facial muscle contraction, leading to reduced muscle tension and visible reduction in the depth of expression wrinkles including crow’s feet and forehead lines. Also stimulates natural collagen and elastin production, increasing skin elasticity and firmness. Acts preventively \u2014 regular use slows skin ageing by inhibiting excessive muscle contractions and preventing formation of new wrinkles. Excellent tolerance across all skin types including sensitive skin. In acne-prone skin, reduces micro-inflammation, supports barrier rebuilding, and may indirectly contribute to reduction of post-acne scars through collagen and elastin stimulation. In scalp application, reduces scalp micro-inflammation to support healthy follicle function, strengthens hair at the root, and improves hair elasticity and resistance to breakage.<\/p>\n

PDRN<\/strong> (Polydeoxyribonucleotide \u2014 Salmon DNA) \u2014 DNA-Level Regenerative Agent<\/em><\/p>\n

A registered and patented therapeutic agent with tissue repair, anti-ischaemic, and anti-inflammatory properties. A naturally occurring building block of DNA that helps repair damaged skin cells and stimulates collagen production through activation of adenosine A2 receptors and the salvage pathway. Accelerates intensive skin repair, reduces visibility of post-acne scars and stretch marks, minimises pores, reduces wrinkles and fine defects, accelerates cellular renewal, stimulates collagen production, and improves skin elasticity and hydration.<\/p>\n

Palmitoyl Tetrapeptide-7<\/strong> \u2014 Anti-inflammatory Collagen Protection Peptide<\/em><\/p>\n

An advanced tetrapeptide with strong anti-inflammatory properties, critical for treating chronic skin inflammation that contributes to collagen and elastin degradation. Stimulates fibroblasts to increase collagen production and protects existing collagen from degradation by matrix metalloproteinases (MMPs). Improves the skin’s protective barrier, supports microcirculation, and is particularly effective in reducing dark circles and puffiness under the eyes.<\/p>\n

Dipeptide<\/strong> \u2014 Collagen Synthesis Stimulator<\/em><\/p>\n

Directly influences collagen synthesis processes by activating fibroblasts, helping to rebuild skin structure and visibly reduce wrinkle depth. Strengthens the skin barrier, exerts anti-inflammatory action, and acts as a natural humectant.<\/p>\n

Arginine<\/strong> \u2014 Collagen Amino Acid & Microcirculation Improver<\/em><\/p>\n

An amino acid playing a key role in protein synthesis including collagen. Supports collagen synthesis, strengthens the skin barrier, exerts anti-inflammatory action, and as a nitric oxide precursor improves microcirculation and delivery of nutrients and oxygen to skin cells. Possesses humectant properties for long-lasting hydration and supports wound healing.<\/p>\n

Arbutin<\/strong> \u2014 Brightening & Antioxidant Agent<\/em><\/p>\n

Inhibits tyrosinase enzyme activity, reducing melanin production in skin cells. Effectively brightens existing pigmentation spots including sun spots, melasma, and post-acne marks, and prevents formation of new ones. Contributes to even skin tone and possesses antioxidant properties protecting against free radical damage. Considered safe for all skin types including sensitive skin, without the irritation risk associated with more aggressive brightening agents.<\/p>\n

Adenosine<\/strong> \u2014 Collagen Stimulator & Anti-aging Agent<\/em><\/p>\n

Naturally occurring in every human body cell, playing a key role in energy and signalling processes. Stimulates fibroblast activity, increasing collagen and elastin production, improving skin elasticity and firmness, and visibly reducing wrinkle depth. Exerts anti-inflammatory and regenerative action and helps maintain proper skin hydration. Protects against UV radiation and environmental pollution damage.<\/p>\n

Butylene Glycol<\/strong> \u2014 Humectant & Active Ingredient Carrier<\/em><\/p>\n

An effective humectant attracting and retaining water in the epidermis for long-lasting hydration. Acts as a solvent and carrier for active ingredients, improving their penetration into the skin and increasing overall formula effectiveness.<\/p>\n

Glycerin<\/strong> \u2014 Hydrating Agent<\/em><\/p>\n

Provides additional hydration support and skin conditioning.<\/p>\n

Hydroxyethylcellulose (HEC)<\/strong> \u2014 Formula Stabiliser & Penetration Support<\/em><\/p>\n

A water-soluble plant-derived polymer acting as a thickener, emulsion stabiliser, and texture improver. Creates an optimal environment for active ingredients, stabilising the formula and ensuring active substances are delivered to the skin with expected potency. Also possesses humectant properties and is well tolerated by sensitive skin.<\/p>\n

1,2-Hexanediol<\/strong> \u2014 Penetration Enhancer & Preservative<\/em><\/p>\n

An organic compound acting as a humectant and solvent. Improves penetration of active ingredients, ensures long-lasting hydration, and is well tolerated across all skin types.<\/p>\n

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\u2705 Indications<\/strong><\/p>\n

    \n
  • Expression wrinkles \u2014 forehead, crow’s feet, perioral area<\/li>\n
  • Static wrinkles and loss of skin firmness<\/li>\n
  • Skin requiring botox-like effect without botulinum toxin<\/li>\n
  • Mesobotox procedures<\/li>\n
  • Corrective treatment following botulinum toxin procedures<\/li>\n
  • Acne-prone skin and post-acne scarring<\/li>\n
  • Hyperpigmentation, melasma, and uneven skin tone<\/li>\n
  • Skin requiring intensive regeneration and repair<\/li>\n
  • Scalp treatments \u2014 inflammatory scalp conditions, hair weakening, hair loss support<\/li>\n
  • Sensitive and reactive skin<\/li>\n<\/ul>\n
    \n

    \u2705 Mechanism of Action<\/strong><\/p>\n

    The preparation acts through four simultaneous pathways. Acetyl Hexapeptide-8 inhibits neurotransmitter release at the neuromuscular junction, relaxing expression muscles and smoothing dynamic wrinkles without muscle paralysis. PDRN activates adenosine A2 receptors and the DNA salvage pathway, stimulating cellular repair and collagen synthesis from the DNA level upward. Palmitoyl Tetrapeptide-7 and Dipeptide reinforce this by protecting existing collagen from enzymatic degradation and directly stimulating fibroblast activity. Arbutin and Adenosine address pigmentation and skin radiance simultaneously. The humectant and penetration-enhancing vehicle components (Butylene Glycol, 1,2-Hexanediol, Glycerin, HEC) ensure optimal delivery and bioavailability of all actives.<\/p>\n

    \n

    \u2705 Treatment Effects<\/strong><\/p>\n

      \n
    • Visible reduction of expression and static wrinkles<\/li>\n
    • Botox-like smoothing effect without toxin<\/li>\n
    • Stimulation of collagen and elastin production<\/li>\n
    • Improved skin elasticity, firmness, and density<\/li>\n
    • Brightening of pigmentation spots and evening of skin tone<\/li>\n
    • Reduction of acne-related inflammation and improvement of post-acne skin<\/li>\n
    • Intensive skin regeneration and repair<\/li>\n
    • Reduction of dark circles and puffiness under the eyes<\/li>\n
    • Improved skin hydration and barrier function<\/li>\n
    • Prevention of new wrinkle formation with regular use<\/li>\n
    • In scalp application: reduced scalp inflammation, healthier follicle environment, stronger hair at the root, improved hair elasticity<\/li>\n<\/ul>\n
      \n

      \u2705 Treatment Areas<\/strong><\/p>\n

        \n
      • Face<\/li>\n
      • Eye area<\/li>\n
      • Neck and d\u00e9colletage<\/li>\n
      • Scalp<\/li>\n<\/ul>\n
        \n

        \u2705 Key Benefits<\/strong><\/p>\n

          \n
        • Botox-like effect without botulinum toxin:<\/strong> Acetyl Hexapeptide-8 delivers neuromuscular relaxation and expression wrinkle reduction through a non-toxic, non-invasive mechanism with no risk of facial asymmetry or muscle freezing.<\/li>\n
        • Mesobotox application:<\/strong> Can be used as a standalone mesobotox treatment or as an enhancer and corrective agent following botulinum toxin procedures.<\/li>\n
        • Dual anti-aging action:<\/strong> Simultaneously addresses wrinkles through neuromuscular relaxation (Acetyl Hexapeptide-8) and through structural protein synthesis stimulation (PDRN, Palmitoyl Tetrapeptide-7, Dipeptide, Adenosine, Arginine).<\/li>\n
        • Brightening included:<\/strong> Arbutin and Adenosine address pigmentation alongside the anti-ageing action, making ToxUp suitable for skin with concurrent discolouration concerns.<\/li>\n
        • Preventive anti-ageing:<\/strong> Regular use slows the ageing process by limiting excessive expression muscle activity, preventing new wrinkle formation.<\/li>\n
        • Scalp versatility:<\/strong> The anti-inflammatory and regenerative properties of the formula extend to scalp application for improved follicle health and stronger hair.<\/li>\n
        • No risk of frozen face:<\/strong> Unlike botulinum toxin, Acetyl Hexapeptide-8 gently moderates muscle contractions without risk of excessive weakening or unnatural immobility.<\/li>\n
        • Broad technology compatibility:<\/strong> Can be combined with RF, laser, ultrasound, and other energy-based technologies post-treatment.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"
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          \n

          Belviso ToxUp \u2014 Botox-like Peptide Mesotherapy Complex<\/strong><\/p>\n<\/div>\n<\/div>\n

          \n
          \n

          An innovative skin care preparation designed to revolutionise the approach to anti-ageing. Enriched with a high concentration of Acetyl Hexapeptide-8, known as Amino-Peptide or the renowned Peptide-Botox, the formula is comparable to applying botox directly to the skin, utilising the power of plant-derived amino acids to deliver significant wrinkle reduction and skin firming. ToxUp helps reduce existing wrinkles and prevents the formation of new ones, offering a dual-directional approach to smooth, youthful skin. The formula is specifically designed to be non-toxic and non-irritating, making it an ideal alternative to traditional botulinum toxin procedures. Contains botulinum protein components that mirror those found in botox but are entirely free of toxins, with rapid skin absorption and visible results without the concerns of negative side effects.<\/p>\n<\/div>\n<\/div>\n

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          \ud83d\udce6 Packaging:<\/strong> 5 ml<\/p>\n<\/div>\n<\/div>\n","protected":false},"featured_media":3936,"comment_status":"open","ping_status":"closed","template":"","meta":{"inline_featured_image":false},"product_brand":[],"product_cat":[69],"product_tag":[100,120,86,89,143,103,118,133,109,125],"class_list":{"0":"post-3598","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-mesotherapy","7":"product_tag-anti-aging","8":"product_tag-botox-like","9":"product_tag-collagen-stimulator","10":"product_tag-firming-lifting","11":"product_tag-mesobotox","12":"product_tag-mesotherapy","13":"product_tag-pdrn","14":"product_tag-pigmentation","15":"product_tag-professional-treatment","16":"product_tag-skin-brightening","18":"first","19":"instock","20":"shipping-taxable","21":"product-type-simple"},"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t