{"id":3705,"date":"2026-04-14T09:05:38","date_gmt":"2026-04-14T07:05:38","guid":{"rendered":"https:\/\/belvisodrhoa.com\/?post_type=product&p=3705"},"modified":"2026-07-06T12:07:45","modified_gmt":"2026-07-06T10:07:45","slug":"pcl-structiva","status":"publish","type":"product","link":"https:\/\/belvisodrhoa.com\/pl\/catalogue\/collagen-stimulator\/pcl-structiva\/","title":{"rendered":"PCL Structiva"},"content":{"rendered":"

\u2705 Active Ingredients<\/strong><\/p>\n

Polycaprolactone (PCL)<\/strong> (3%) \u2014 Long-Acting Collagen Biostimulator<\/em><\/p>\n

A long-acting biostimulator of type I and type III collagen. PCL microspheres measuring 25 to 50 \u00b5m are distributed evenly throughout the mesoderm, where they release gradually over 12 to 18 months, continuously stimulating neocollagenesis. This sustained release increases skin density, rebuilds the 3D architecture of the dermis, delivers a lifting effect improving facial contour (V-line effect), and reduces static wrinkles and skin laxity. The 3% concentration represents the optimal dosage for effective yet safe biostimulation.<\/p>\n

Acetyl Hexapeptide-8<\/strong> \u2014 Neuromodulatory Botox-like Peptide<\/em><\/p>\n

Part of the Bio-Active Peptides Complex (2% total). Reduces expression muscle tension through a botox-like mechanism, smoothing dynamic wrinkles without causing muscle paralysis.<\/p>\n

Palmitoyl Pentapeptide-4<\/strong> \u2014 Collagen-Stimulating Peptide<\/em><\/p>\n

Part of the Bio-Active Peptides Complex. Activates fibroblasts to synthesise collagen and elastin, improves microcirculation, and supports cellular renewal. Works synergistically with PCL to amplify the collagen-stimulating effect.<\/p>\n

EGF \u2014 Oligopeptide-1<\/strong> (Epidermal Growth Factor) \u2014 Cellular Regeneration Factor<\/em><\/p>\n

One of the most important natural growth factors used in aesthetic medicine. In the Belviso PCL Structiva formula, EGF acts complementarily to PCL and the biomimetic peptides \u2014 PCL delivers long-term collagen stimulation, the peptides deliver the botox-like effect, and EGF regenerates and accelerates cellular renewal following injection, providing rapid smoothing and radiance post-treatment.<\/p>\n

Mannitol<\/strong> (1%) \u2014 Natural Antioxidant & Osmoprotectant<\/em><\/p>\n

A natural antioxidant and osmoprotectant that protects cells from oxidative stress, reduces post-treatment oedema and redness, stabilises the PCL structure, and extends the bioactivity of the preparation.<\/p>\n

Sodium Hydroxypropyl Methylcellulose (HPMC)<\/strong> (1%) \u2014 Viscosity Agent & Barrier Support<\/em><\/p>\n

Responsible for the appropriate viscosity and consistency of the preparation. Facilitates even delivery of active substances, forms a protective film on the skin surface, and supports rebuilding of the hydrolipidic barrier.<\/p>\n

\n

\u2705 Indications<\/strong><\/p>\n

    \n
  • Loss of skin tension, density, and elasticity<\/li>\n
  • Dynamic (expression) wrinkles<\/li>\n
  • Static wrinkles and skin laxity<\/li>\n
  • Loss of facial contour definition<\/li>\n
  • Skin requiring long-term structural rebuilding<\/li>\n
  • Skin in need of immediate revitalisation alongside collagen stimulation<\/li>\n
  • Anti-aging prevention and maintenance<\/li>\n<\/ul>\n
    \n

    \u2705 Mechanism of Action<\/strong><\/p>\n

    The preparation acts through three complementary and simultaneous mechanisms:<\/p>\n

      \n
    • PCL<\/strong> is distributed as microspheres in the mesoderm and releases gradually over 12 to 18 months, providing continuous stimulation of neocollagenesis, increasing skin density, and rebuilding the 3D dermal architecture.<\/li>\n
    • Biomimetic peptide complex<\/strong> reduces expression muscle tension (botox-like effect), activates fibroblasts for collagen and elastin synthesis, improves microcirculation, and accelerates cellular renewal.<\/li>\n
    • EGF<\/strong> complements the above by accelerating post-treatment cellular regeneration and delivering an immediate smoothing and brightening effect.<\/li>\n<\/ul>\n

      Mannitol protects the active components from oxidative degradation and reduces post-treatment reactivity, while HPMC ensures consistent and even delivery of all actives.<\/p>\n

      \n

      \u2705 Treatment Effects<\/strong><\/p>\n

        \n
      • Botox-like effect without botulinum toxin<\/li>\n
      • Long-term stimulation of type I and type III collagen<\/li>\n
      • Improved skin tension, density, and elasticity<\/li>\n
      • Reduction of dynamic and static wrinkles<\/li>\n
      • Restoration of natural facial contour \u2014 V-line effect<\/li>\n
      • Visible refreshing effect from 7 to 10 days post-treatment<\/li>\n
      • Full effect from 4 to 6 weeks post-treatment<\/li>\n<\/ul>\n
        \n

        \u2705 Treatment Areas<\/strong><\/p>\n

          \n
        • Face<\/li>\n
        • Eye and perioral area<\/li>\n
        • Neck<\/li>\n
        • D\u00e9colletage<\/li>\n<\/ul>\n
          \n

          \u2705 Key Benefits<\/strong><\/p>\n

            \n
          • Dual-action formula:<\/strong> Delivers simultaneous collagen biostimulation (long-term) and botox-like expression wrinkle reduction (immediate) in a single preparation.<\/li>\n
          • PCL at 3% \u2014 sustained release over 12 to 18 months:<\/strong> A single treatment course continues working long after the sessions are complete, providing progressive improvement without the need for frequent repeat treatments.<\/li>\n
          • Optimal microsphere size:<\/strong> PCL microspheres of 25 to 50 \u00b5m ensure even distribution throughout the mesoderm and predictable, controlled release.<\/li>\n
          • EGF for immediate post-treatment radiance:<\/strong> The epidermal growth factor ensures visible skin smoothing and brightness from the first days following treatment while the long-term PCL action is still establishing.<\/li>\n
          • Mannitol protection:<\/strong> The natural antioxidant and osmoprotectant reduces post-treatment swelling and redness while stabilising the PCL structure and extending its bioactivity.<\/li>\n
          • Multiple application technique compatibility:<\/strong> Can be applied via manual needle mesotherapy, multineedle cartridge, microneedling, or Vital Injector 2 \u2014 adaptable to different clinical preferences and treatment areas.<\/li>\n
          • Combination protocol versatility:<\/strong> Can be combined in alternating protocols with Belviso StrongLift GHK, Belviso Bocutox NeuroLift Forte, or used in a mesobotox protocol.<\/li>\n<\/ul>\n
            \n

            \u2705 Post-Treatment Recommendations<\/strong><\/p>\n

              \n
            • Cool the skin following treatment.<\/li>\n
            • Avoid sauna, sun exposure, and makeup for 24 to 48 hours.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

              Belviso PCL Structiva \u2014 Next-Generation Collagen Stimulator<\/strong><\/p>\n

              An advanced next-generation collagen stimulator with a simultaneous botox-like and biorevitalising effect. Through the synergy of PCL and biomimetic peptides, the preparation works on multiple levels \u2014 from immediate skin tightening through to long-term rebuilding of collagen structures. The formula delivers progressive results: a visible refreshing effect from 7 to 10 days after treatment and a full effect from 4 to 6 weeks.<\/p>\n

              \ud83d\udce6 Packaging:<\/strong> 5 x 6ml<\/p>\n","protected":false},"featured_media":3706,"comment_status":"open","ping_status":"closed","template":"","meta":{"inline_featured_image":false},"product_brand":[],"product_cat":[200,74,73],"product_tag":[100,104,120,86,121,89,103,119,271,109,106,270],"class_list":{"0":"post-3705","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-collagen-stimulator","7":"product_cat-plla-pcl-caha","8":"product_cat-skinbooster","9":"product_tag-anti-aging","10":"product_tag-biostimulation","11":"product_tag-botox-like","12":"product_tag-collagen-stimulator","13":"product_tag-egf","14":"product_tag-firming-lifting","15":"product_tag-mesotherapy","16":"product_tag-pcl","17":"product_tag-plla-pcl-caha","18":"product_tag-professional-treatment","19":"product_tag-skin-densification","20":"product_tag-skinbooster","22":"first","23":"instock","24":"shipping-taxable","25":"product-type-simple"},"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t