{"id":3813,"date":"2026-04-14T17:19:13","date_gmt":"2026-04-14T15:19:13","guid":{"rendered":"https:\/\/belvisodrhoa.com\/?post_type=product&p=3813"},"modified":"2026-07-06T12:06:03","modified_gmt":"2026-07-06T10:06:03","slug":"5bap-propn","status":"publish","type":"product","link":"https:\/\/belvisodrhoa.com\/pl\/catalogue\/volumetry\/5bap-propn\/","title":{"rendered":"5BAP ProPN"},"content":{"rendered":"

\u2705 Active Ingredients<\/p>\n

HMW-HA \u2014 High Molecular Weight Hyaluronic Acid (32 mg)<\/strong> Forms a protective film on the skin surface, providing a biological lifting effect. Maintains long-term hydration by limiting transepidermal water loss (TEWL).<\/p>\n

LMW-HA \u2014 Low Molecular Weight Hyaluronic Acid (32 mg)<\/strong> Penetrates deeper skin layers, stimulating fibroblast activity. Improves skin elasticity and resilience, giving it a fresh and rested appearance.<\/p>\n

PN \u2014 Polynucleotides (45 mg \/ 3 ml)<\/strong> Potent natural biostimulators. Activate repair processes, improve microcirculation, stimulate type I and III collagen synthesis, and exert antioxidant action. Result: skin densification, improved tension, and youthful radiance.<\/p>\n

\n

\u2705 Indications<\/p>\n

    \n
  • Loss of skin firmness and elasticity on the face, neck, and d\u00e9colletage<\/li>\n
  • Photoaging, loss of radiance, and uneven skin tone<\/li>\n
  • Nasolabial folds, marionette lines, and loss of jawline definition<\/li>\n
  • Loss of tension in the chin and zygomatic area<\/li>\n
  • Patients under 40 with genetically weak retentive ligaments and early tissue ptosis tendency<\/li>\n
  • Vertical neck wrinkles and platysmal bands<\/li>\n
  • Skin requiring biological lifting without volume addition<\/li>\n<\/ul>\n
    \n

    \u2705 Mechanism of Action<\/p>\n

    Belviso 5BAP ProPN acts as a biological restructurer rather than a volumetric filler, activating a series of repair processes when injected into strategic points.<\/p>\n

    HMW-HA<\/strong> creates a hydroelastic film on the skin surface, providing biological lifting tension and limiting TEWL.<\/p>\n

    LMW-HA<\/strong> penetrates deeper into the dermis, stimulating fibroblasts, improving elasticity, and deeply hydrating the skin tissue.<\/p>\n

    Polynucleotides (PN)<\/strong> act as a powerful biostimulator: increasing collagen type I and III synthesis, remodeling the extracellular matrix (ECM), promoting angiogenesis, and providing antioxidant protection \u2014 resulting in skin thickening and improved tissue retention around ligament attachment points.<\/p>\n

    The synergy of dual hyaluronic acid (intensive hydration and elasticity) and polynucleotides (regeneration and skin densification) provides natural tissue lifting without excessive volume.<\/p>\n

    \n

    \u2705 Treatment Effects<\/p>\n

      \n
    • Significant improvement of skin quality: density, tension, elasticity, and radiance<\/li>\n
    • Natural tissue lifting without volume addition<\/li>\n
    • Improvement of facial contour and symmetry<\/li>\n
    • Reduction of fatigue signs and skin dehydration<\/li>\n
    • Smoothing of nasolabial folds, marionette lines, and loss of jawline definition<\/li>\n
    • Improvement of neck skin tension and smoothing of vertical wrinkles (platysmal bands)<\/li>\n
    • Biorevitalization with a neck tightening effect<\/li>\n
    • Increased skin thickness through PN-driven collagen and elastin regeneration<\/li>\n
    • Evening of skin tone and improvement of skin structure in the supraclavicular zone<\/li>\n
    • Long-term effect: slowing of tissue laxity processes<\/li>\n<\/ul>\n
      \n

      \u2705 Treatment Areas<\/p>\n

        \n
      • Face (zygomatic area, jawline, nasolabial folds, temples, chin)<\/li>\n
      • Neck<\/li>\n
      • D\u00e9colletage<\/li>\n
      • Eye area (with reduced volumes and greater point spacing)<\/li>\n<\/ul>\n
        \n

        \u2705 Key Benefits<\/p>\n

        Beyond Profhilo \u2014 PN-enhanced bioremodeling:<\/strong> Like Profhilo, it utilizes the synergistic action of two hyaluronic acid fractions (HMW-HA + LMW-HA), but goes further by adding polynucleotides that intensify regenerative processes and collagenogenesis, making it a unique tool for biological lifting and cellular-level skin reconstruction.<\/p>\n

        Profiling without volume:<\/strong> Acts on ligament attachment points and structural support zones to improve the lifting vector and delay tissue ptosis, without adding volume or changing facial proportions.<\/p>\n

        Belviso Ligament Concept:<\/strong> An intelligent ligament protocol acting in three skin layers. All strategic support points work along key anatomical structures, reinforcing the zygomatic ligament, providing gentle lifting of the masseter area, harmonizing facial oval, and along the platysma on the neck, activating collagen synthesis and smoothing vertical muscle bands.<\/p>\n

        3 ml volume:<\/strong> Enables not only the classic 5BAP protocol but also additional stimulation of strategic facial zones such as the jawline, nasolabial folds, and temples, as well as comprehensive neck and d\u00e9colletage coverage.<\/p>\n

        Compatible with botulinum toxin (NeckLift protocol):<\/strong> When combined with 40 units of botulinum toxin injected into the platysma, results are smoother and longer-lasting \u2014 the preparation improves tissue quality while the toxin reduces dynamic pulling forces, changing the biomechanical environment and accelerating remodeling.<\/p>\n

        \n

        \u2705 Post-Treatment Recommendations<\/p>\n

          \n
        • Apply cooling for 10 to 15 minutes after treatment.<\/li>\n
        • Avoid massage, sauna, and physical exercise for 24 to 48 hours after treatment.<\/li>\n
        • Makeup may be applied after 12 to 24 hours.<\/li>\n
        • When botulinum toxin is used in combination: effect begins at 3 to 7 days, peak at day 14.<\/li>\n<\/ul>\n
          \n

          \u2705 Contraindications<\/p>\n

            \n
          • Pregnancy and breastfeeding<\/li>\n
          • Active skin infections in the treatment area<\/li>\n
          • Neuromuscular diseases (myasthenia gravis, Lambert-Eaton syndrome)<\/li>\n
          • Active autoimmune conditions without stabilization<\/li>\n
          • Coagulation disorders<\/li>\n
          • Anticoagulant therapy (consult regarding appropriate discontinuation)<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

            Belviso 5BAP ProPN \u2014 Dual HA Hydration & PN-Powered Regeneration<\/strong> An innovative next-generation bioremodeling preparation combining two fractions of hyaluronic acid with a high concentration of regenerative polynucleotides. It provides dual hydration, biological lifting, and intensive structural skin reconstruction while simultaneously stimulating neocollagenesis and angiogenesis. Unlike volumetric fillers, it acts as a biological restructurer that activates natural repair processes, delivering natural tissue lifting without adding volume. For professional use only.<\/p>\n

            \ud83d\udce6 Packaging: 3 ml per ampoule.<\/p>\n","protected":false},"featured_media":3929,"comment_status":"open","ping_status":"closed","template":"","meta":{"inline_featured_image":false},"product_brand":[],"product_cat":[70],"product_tag":[100,171,86,172,89,173,118,108,109,106,123],"class_list":{"0":"post-3813","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-volumetry","7":"product_tag-anti-aging","8":"product_tag-bioremodeling","9":"product_tag-collagen-stimulator","10":"product_tag-dual-ha","11":"product_tag-firming-lifting","12":"product_tag-necklift","13":"product_tag-pdrn","14":"product_tag-polynucleotides","15":"product_tag-professional-treatment","16":"product_tag-skin-densification","17":"product_tag-volumetry","19":"first","20":"instock","21":"shipping-taxable","22":"product-type-simple"},"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t