Exocell

Belviso ExoCell — Stabilized Exosome Complex

An advanced stabilized exosome preparation derived from human stem cell conditioned media. ExoCell contains nanovesicles (30–150 nm) composed of a lipid bilayer membrane encapsulating RNA, miRNA, proteins, and DNA — the same building blocks as the human cell membrane, ensuring exceptional tissue permeability. Delivers a powerful regenerative signal directly to skin cells, stimulating collagen synthesis, elastin production, barrier repair, and comprehensive skin rejuvenation. Approximately 16 times more potent than standard exosome preparations on the market, with approximately 1.8 times greater skin cell absorption.

📦 Packaging: 1 kit = 2 ampoules — Blanc HA (5 ml liquid) + Blanc Powder (50 mg stabilized exosomes)

✅ Active Ingredients

Blanc Powder — Stabilized Exosomes (50 mg)

Human Stem Cell Conditioned Media (100,000 ppm) Conditioned media from human stem cells containing a rich concentration of growth factors, cytokines, and regenerative signals. Directly stimulates fibroblast activity, collagen and elastin synthesis, and skin cell renewal.

Human Amniotic Fluid Cell Extract Conditioned Media (886,000 ppm) An exceptionally concentrated conditioned media from human amniotic fluid cells. Provides an intensive regenerative signal supporting skin matrix reconstruction and anti-aging processes.

Sodium Hyaluronate Deeply hydrates and supports the penetration of the exosome complex into the skin tissue.

Hydrolyzed Collagen Provides building blocks for skin matrix reconstruction, supports firmness and density.

Trehalose A natural stabilizing sugar that protects the exosome structure during storage, ensuring stability at room temperature and preserving full biological activity.

Blanc HA — 5 ml Liquid Base

Water + Sodium Hyaluronate The liquid dissolving base for the Blanc Powder. Provides additional hydration and ensures optimal mixing and delivery of the exosome complex.

✅ What Are Exosomes?

Exosomes are nanovesicles (30–150 nm in diameter) composed of a lipid bilayer membrane surrounding RNA, miRNA, proteins, and DNA. They are extracellular vesicles produced by mesenchymal stem cells and participate in cell-to-cell communication. Because exosomes circulate in body fluids, they can transmit information not only to local cells but also to distant ones. They are considered potential biomarkers and therapeutic agents for a wide range of conditions. Recent research has demonstrated their effectiveness in skin defects such as aging, atopic dermatitis, and wound healing. Korean scientists have proven it is possible to isolate and deliver these beneficial signals directly — without the stem cells themselves.

The stabilized exosomes in Belviso ExoCell are more durable than those found in other exosomal preparations, allowing storage at room temperature before mixing and in the refrigerator for up to 2 weeks after preparation.

✅ Why ExoCell is Different

• Approximately 16 times more potent than standard exosome preparations
• Approximately 1.8 times greater absorption into dermal skin cells compared to general exosomes
• Superior skin penetration — high concentration of exosomes reaches the dermal layer where key cells and matrix factors for skin regeneration are present
• Contains various extracellular matrix (ECM) components that synthesize collagen in the dermal layer
• Stabilized formula — stable at room temperature before mixing, no cold chain required
• Stimulates filaggrin production — the key protein in the outermost skin layer that binds keratin, increases physical support, and strengthens the skin barrier

✅ Mechanism of Action

Exosomes penetrate the skin through lipids between pores, sweat glands, and keratinocytes, reaching deep into the dermal layer. Once absorbed into skin cells, they deliver a concentrated regenerative signal — growth factors, miRNA, and regenerative proteins — directly stimulating fibroblasts to increase collagen and elastin synthesis, activating the extracellular matrix, and promoting cell renewal. ExoCell exosomes fuse easily with dermal cells, achieving approximately 1.8 times greater cell absorption than standard exosomes. Filaggrin production is increased, strengthening the skin barrier and restoring the skin surface from a damaged state to near-normal, as confirmed in the KeraSkin epidermal skin model.

✅ Treatment Effects

• Up to 6-fold increase in skin collagen levels
• Up to 300% increase in elastin levels
• 50 to 70% reduction in fine lines, wrinkles, and age spots
• Significant improvement in skin tone and hydration
• Marked reduction of erythema, redness, and skin irritation
• Improvement of vascular and sensitive skin condition
• Improved skin texture and visible reduction of pore size
• Improvement of scar appearance
• Immediate facelift effect visible after the first treatment
• Results continue to improve over weeks and months as collagen production increases
• Benefits can last up to 18 to 24 months

✅ Key Benefits

Exceptional potency: Approximately 16 times more potent than standard exosome preparations. Approximately 1.8 times greater dermal cell absorption for faster and stronger results.

Stabilized formula: Unlike standard exosomes which degrade quickly, ExoCell’s stabilized powder format remains stable at room temperature before mixing. After mixing, stable in the refrigerator for up to 2 weeks.

Comprehensive regeneration: Simultaneously stimulates collagen, elastin, and filaggrin production while repairing the skin barrier, improving hydration, and reducing inflammation.

Suitable for sensitive and vascular skin: Significantly reduces erythema, redness, and irritation. Suitable for atopic, rosacea-prone, and post-procedure skin.

Immediate and long-lasting results: Facelift effect visible immediately after treatment. Results continue to improve over following weeks and months, with benefits lasting up to 18 to 24 months.

Highly versatile — multiple application methods: Compatible with needle mesotherapy, Dermapen, microneedling, Vital Injector, mesogun, cavitation peeling, sonophoresis, microdermabrasion, and ultrasound.